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Research

We are constantly involved in research efforts that strive to advance veterinary medicine.  This research includes internal projects, graduate studies, and external sample submissions.

Current Research Projects

  • Small Animal E. coli Antimicrobial Resistance Survey (SAECARS)

Project Description: Epidemiological investigation to help delineate risk factors and current patterns of antimicrobial resistance in clinical canine and feline E. coli.

  • Pharmacokinetic and Pharmacodynamic study of Fosfomycin in Canines.

Project Description: Measuring plasma drug concentrations after oral and IV administration of Fosfomycin to canines and looking for common side effects or complications.

  • FRET-based, High-level Fluoroquinolone Resistance in E. coli Assay

Project Description: Development and validation of a rapid, FRET-based, quantitative PCR Assay to identify High-level Fluoroquinolone Resistance in e. coli isolated from canine urine.

Analytical Service

The Clinical Pharmacology Lab offers Analytical Service that can be used for research projects consisting of multiple samples and potential data analysis.  This is different from Therapeutic Drug Monitoring on clinical patients.

Cost:

Our costs generally range from $25-$200 depending on number of samples and ease of detection which is based on several factors (extraction, reagent costs, specificity [e.g. parent compound, metabolites, or enantiomers], sensitivity, previously developed method).  For example, an assay that is currently being run in our laboratory is likely to be less expensive than an assay that must be fully developed and validated for a new compound or species.

Submission Process:

To request a quote for analytical service, simply complete this form and submit by fax, email, or mail.  We will respond with an estimate of price and turn-around time.

Test List:

The Clinical Pharmacology Lab has already developed the following assays:

Assay

Method

Species

Media

Amikacin

Immunoassay

Canine, Feline

Serum, Plasma, Buffer

Bromide (Potassium/Sodium)

Spectrophotometer

Canine, Avian

Serum, Plasma, Buffer, Solutions, Capsules

Carvedilol

HPLC

Canine, Feline

Serum, Plasma, Capsules, Buffer

Clindamycin

HPLC

 

Buffer

Cyclosporine

Immunoassay

Canine, Feline

EDTA Whole Blood

Enrofloxacin

HPLC

Canine, Feline, Equine

Serum, Plasma, Buffer

Diazepam

HPLC

Feline

Serum, Plasma

Dilantin (Phenytoin)

Immunoassay

Canine

Serum, Plasma

Digoxin

Immunoassay

Canine, Equine

Serum, Plasma

Gabapentin

Immunoassay

Canine

Serum, Plasma

Gentamicin

Immunoassay

Canine

Serum, Plasma

Keppra (Levetiracetam)

Immunoassay

Canine, Feline

Serum, Plasma

Lidocaine

Immunoassay

Canine, Feline

Serum, Plasma

Meloxicam

HPLC

Hawk, Owl

Serum, Plasma

Methimazole

HPLC

Feline

Serum, Plasma, Buffer, Suspensions

Metronidazole

HPCL

Feline

Serum, Plasma, Buffer, Suspensions

Metronidazole Benzoate

HPLC

Feline

Serum, Plasma, Buffer, Suspensions

Phenobarbital

Immunoassay

Canine, Feline

Serum, Plasma

Prednisone

HPLC

Feline

Serum, Plasma, Buffer, Suspensions

Prednisolone

HPLC

Feline

Serum, Plasma, Buffer, Suspensions

Theophylline

Immunoassay

Canine, Feline

Serum, Plasma

Tramadol (and metabolites)

HPLC

Equine

Serum, Plasma

Vancomycin

Immunoassay

Canine, Feline

Serum, Plasma

Voriconazole

HPLC

Hawks

Serum, Plasma

Zonisamide

Immunoassay

Canine, Feline

Serum, Plasma

Auburn University | College of Veterinary Medicine | Auburn, Alabama 36849 | (334) 844-4546
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